Oh, I can feel the flames of public disapproval hotly licking my little pink toes under the desk just for typing that outrageous title. One thing that we are not allowed to admit in our culture is that obesity is anything but a failure of will power among low class, trailer-living, Springer-loving, fried Coca-Cola-scarfing, Mountain Dew-guzzling harbingers of the apocolypse. But guess what? Obesity is a chronic disease and willpower has very little to do with curing it.
I was cruising the internet trying to find out if there is anything new with any of my favorite researchers. I found a three part article from blogger Maggie Mahar that talks about the PBS documentary Fat: What No One Is Telling You – a documentary that you must see. The entire show is online. Anyway, Miss Mahar follows up with a few of the researchers interviewed in the documentary. In the first entry, she talks about the variety of characters the film covers – the somewhat zaftig redhead who exercises three hours a day to keep the weight off, the former athlete who gained 125 pounds when she went to work for Microsoft, and the slender producer’s obese twin brother who is going in for a gastric bypass.
Although many physicians still “believe that obesity is caused by eating too much and not exercising enough, such thinking is too simplistic,” says Dr Robert Lustig, of the Division of Pediatric Endocrinology at the University of California, San Francisco. An expert in the field, he knows that obesity is “a chronic condition.” And we don’t have a cure.
This is why, even when patients enter medically supervised weight-loss programs, and stick with the rules, Lustig explains, “95 percent” regain whatever pounds they lose.
“This is not simply ‘energy in and energy out.’ If it were we would have solved it a long time ago,” says Harvard’s Dr. Lee Kaplan, who heads the Weight Reduction Program at Mass General Hospital and has established a new, comprehensive basic and clinical research program.
So what jumps out at me here is the statement that obesity is a “chronic problem” and Maggie’s reflection that we “don’t have a cure’. In addition, that 95% of patients that enter medically supervised weight loss programs, regain whatever weight they lose. 95% – that’s a staggering rate of failure. We know this to be true from our own experience and the experience of our family and friends, and the experience of the celebrities who wrestle with obesity.
She then touches on a review of the film from the Amazon website that gets at something that I think is incredibly important – namely, the degree to which we attempt to control the actions of obese people with shaming devices. I see it in discussions of weight loss surgery all the time. Obese people are shamed away from weight loss surgery all the time by the insistence that surgery is taking the easy way out – as if people must be saddled with the most difficult way possible to lose weight in order to restore their lost morality. Weight loss surgery patients live longer lives and happier lives than obese people who attempt to lose weight through diet and exercise. Attempting to shame someone out of a procedure that will adds years to their life and volumes of joy is a truly destructive and sadistic impulse.
“I happened upon this movie on PBS when I was on a business trip, and it essentially helped to kick-start my journey into a healthier lifestyle, where I have lost 40 lbs already in a 150lb long term goal,” the reviewer wrote.
“I remember being deeply and personally moved by the stories, but it was also a game-changing flood of information about the latest biological research that did the trick for me. It allowed me to see the issue not in terms of will power and laziness (as is all too common in popular culture as well as years of medical haranguing), but in terms of physical compulsion akin to and even surpassing opiate addiction.
“Why was this new information so critical in my current success, where previously I had tried and failed? It is definitely that it shatters the myth that weight loss is as simple as consuming less than you expend—a glib and harmful misstatement of the problem as profound as saying that beating heroin addiction is as simple as going cold turkey. You’d think that learning exactly how hard it is, really, to lose weight would be discouraging, but it was exactly the opposite. After years of people, including my doctor and nutritionist, breezily tossing off advice and plans of action, I finally learned what I was up against.
Then I declared war on it.”
In Part II, she talks about how obesity is a disease where the body rejects the cure. I bet no one has ever said that to you before.
If you have ever dieted you may already know that, once you lose some weight, your metabolism slows down and you burn fewer calories. For all your body knows, you are stranded on a desert island, starving to death. So it tries to “help.” The brain is wired to eat and store fat to protect against starvation. In fact, when you lose weight, the human body has redundant systems to try to save you. That’s how the human species has survived.
She discusses the contributions of Dr. Jeffrey Friedman, an obesity researcher at Rockefeller University, to understanding our modern dilemma:
Friedman is famous for his 1994 discovery of the gene that codes for leptin. And for a brief moment in the mid-1990s, the MIT Technology Review explains, “leptin seemed to be a potential wonder cure for obesity.” Researchers hoped that leptin injection would turn up the POMC neuron that inhibits hunger. But leptin injections work for only a small percentage of the obese. It turns out that the majority [of obese people] do produce leptin, but their bodies actually resist the effects of the hormone by blocking its ability to turn up the hunger-suppressing action of the POMC neuron. So their appetites remain large, and they keep eating—and gaining weight—until they reach the point at which the resistance stops. Where that point lies, Friedman believes, is determined by genetic makeup.
Ahhh, genetics. The one thing that we are never allowed to blame our obesity on. Of course, we are willing participants in the deception that genetics are irrelevant because if they are irrelevant, then we still have some hope of getting our weight back to normal and maintaining it.
Some people appear to be hardwired to be particularly ravenous. When access to food is unlimited, say hunger-gene experts, these people can will themselves to eat less, but their efforts will almost inevitably be overridden by the far more powerful force of genetics. Studies show that invariably, weight loss is followed by weight gain, making obesity a life-long struggle. “You just have to keep falling off the horse and getting back on again,” says one woman who appears in “Fat.” A physician in the film points out that trying to continue eating less is like trying to run upstairs without breathing faster. “You can do it for a while, but not for that long.”
She goes on to discuss gastric bypass surgery and how it impacts the communication between the brain and the gut:
At Mass General, Dr. Lee Kaplan agrees: “We have two brains—in the stomach and ‘upstairs.’ The brain in the gut can disturb the brain in the head.”
“Neuro-chemical signals that flow between the two brains,” Kaplan adds and we have discovered that gastric bypass surgery (a.k.a. “stomach-stapling”) interrupts that flow.
Until recently, physicians believed that patients lost weight because the surgery reduced the size of the stomach, forcing them to eat less. But once again, it’s not that simple. Researchers performing gastric bypass surgery on rats have discovered that the surgery severs nerves in the bowel that communicate with the brain—and that this is tied to weight loss.
In Part III of her article, we learn a little bit about the mystery of exercising and dieting but not losing weight even as we get more fit. Turns out that’s good for us as well:
Nevertheless, for those who cannot lose weight, “Exercise without weight loss is an effective strategy for obesity reduction” according to a study published in the Journal of Applied Physiology in 2005.”
What exactly does “obesity reduction without weight loss” mean? The obese men who participated in aerobic exercise, five times per week for 60 min, did not shed pounds. The study was designed to make sure that they wouldn’t: “To allow us to test the hypothesis that significant obesity reduction could occur despite the absence of change in body weight, all subjects were asked to maintain body weight, and they consumed the calories required to compensate for the energy expended during the exercise sessions,” the researchers explain.
Nevertheless, both the obese men and the control group of lean men who participated in the study watched their waist circumference shrink. Cardio-respiratory fitness increased in both groups, as did skeletal muscle with total fat was reduced.
These changes were roughly equal in both groups. But when it came time to measure abdominal fat, reductions in the obese group were significantly greater.
As the articles closes, she includes this observation:
I would add only that our obsession with whether or not people meet cultural norms for beauty—rather than whether they are happy and healthy—fuels the prejudice against obesity that can make even physicians cruel when their patients fail to lose weight. As the public health nurse in “Fat” observes: “These are free-range fat people, just trying to do their best in a culture that hates them.”
I hope you watch the documentary. Use this information to move forward in your life. Why should you eat right and exercise even if you aren’t losing weight? Because it is good for you and you’ll be happier, healthier and you will live longer. But also, once you understand that 95% of people who enter a medically supervised weight loss program fail to keep the pounds off, you can quit feeling guilty and simply get on with your life. If you’re more than 50 pounds overweight, it’s time to think about weight loss surgery. If you were going to be in that 5% who kept weight off, you’d probably know by now. If you have to give dieting one last shot, do so and do it with everything that you’ve got. Call your doctor, not Jenny Craig. Get the best advice you can. Get out and exercise, and throw any junk food you have out. And if it fails one more time, make the call about weight loss surgery.